PDGFR BETA REARRANGEMENT T(5Q33), HEPARIN BLOOD

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NABL Cap Accredited    
This test detects rearrangements involving the PDGFRB gene located at chromosome 5q33, commonly associated with myeloid and lymphoid neoplasms accompanied by eosinophilia. Identifying this abnormality is crucial for accurate diagnosis and for guiding targeted therapy decisions. Patients with PDGFRB rearrangements typically respond well to tyrosine kinase inhibitors such as imatinib. Metropolis Healthcare performs this test using sensitive molecular methods to ensure reliable detection and clinical relevance

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Price: Rs. 5,405.00

Sample Type: Sodium Heparin Blood

Fasting Not Required


Notes: T0018

Frequently Asked Questions (FAQ's):

What does this test detect?
It identifies genetic rearrangements involving the PDGFRB gene at chromosome 5q33.

Why is this test done?
To diagnose specific myeloid or lymphoid neoplasms, especially those presenting with eosinophilia.

What sample is required?
A heparin blood sample is used for analysis.

Is any preparation needed?
No fasting or special preparation is necessary.

How is the test performed?
Using molecular techniques such as FISH or RT-PCR to detect PDGFRB gene rearrangements.

Who should take this test?
Individuals with persistent eosinophilia or suspected myeloid/lymphoid neoplasms.

Can the results guide treatment?
Yes, PDGFRB-positive cases often show excellent response to targeted therapy like imatinib

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